top of page

Best leaving groups for organic reactions?


Most often encountered leaving groups are halogens (Group17). The larger the atomic radius the better of a leaving group halogen is and therefore, I- > Br-> Cl-

Water and OTs are great leaving groups as well.

Thus, according to the David Klein book here is the list of best to worse leaving groups.

Organic chemistry tutor NYC

0 comments

Ready For Chemistry Tutoring?

I tutor all levels of chemistry including general and organic chemistry.

Click To Learn More

bottom of page