Chapter 19: Enolate Anions and Enamines
Table of Contents:
Enols and Enolate Ions
Aldol reaction is one of the most important reactions in this chapter and in semester 2 of organic chemistry. This reaction can occur under basic or acidic conditions.
Under Basic conditions
Under Acidic conditions
Mayya's Trick: How to predict the product of Aldol Condensation
Draw two molecules of the starting material and align =O of one with alpha carbon of the other
Get rid of =O and connect the carbon that had =O with the alpha carbon on another molecule through a double bond
There is also Crossed and Intramolecular Aldol Reactions. Crossed aldol is when instead of attacking itself, the enol or enolate attack another molecule of ketone or aldehyde. Intramolecular aldol is when one end of the molecule attacks another end of the molecule, forming a ring.
Mayya's Trick on how to predict reactants if the product of aldol condensation is given