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What is the major product in the following reaction?

What is the major product in the following reaction?


Solution:

We have a tertiary substrate (bromine is attached to carbon which is attached to three other carbons) and a strong base, OH-. Please note KOH consists of K+ and OH-. OH- is a strong base. Therefore, E2 would be the major reaction, resulting in a double bond. We always want to make the most substituted double bond, making choice D the correct answer.









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